Scientists are examining what internal, nanometer-sized suitcases called “exosomes” are carrying when they arrive at the scene of an acute kidney injury. These injuries can result from a car accident or even a severe infection. While many people fully recover, others are left with permanent kidney damage or worse. Tubules, where our kidneys absorb needed items like water and salt, before passing liquid waste along to the bladder, are a major site for acute kidney damage. Scientists have found exosomes are key to both construction and repair of tubules. They are looking at how, where and how many exosomes are produced, what cargo they carry and which content aids recovery. The goal is to one day pack a recovery suitcase for our kidneys.
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